Description
Structural component of the gap junctions and the hemichannels involved in the ATP release and nucleotide permeation (PubMed: 16908669, PubMed: 20829356, PubMed: 30918116). May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis (PubMed: 16908669). Plays a critical role in oogenesis (PubMed: 30918116)